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Acetyl-CoA carboxylase



Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyses carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes, whereas it is a large, multi-domain enzyme in most eukaryotes.



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