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Dale's principle



Dale's Principle (or Dale's Law) was postulated by the English neuroscientist Henry Hallett Dale and it states that, although different neurotransmitters can be produced at different synapses within the brain, individual neurons are capable of releasing only one neurotransmitter from its axonal terminal. Dale's Principle has been shown to be false because many synapes release neuropeptides as well as amino acids or amines.



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