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FAAH



Fatty acid amide hydrolase is an integral membrane protein that hydrolyzes bioactive amides including the endocannabinoid anandamide (an agonist of cannabinoid receptors and TRPV1 vanilloid receptors) and agonists of the peroxisome proliferator-activated receptors such as N-oleoylethanolamine and N-palmitoylethanolamine to free fatty acid and ethanolamine. It is the primary terminator of N-acyl ethanolamines in addition to the less-well studied N-acyl taurines.



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