Encyclopedia > G > G-protein coupled receptor kinases
G-protein coupled receptor kinases
G-Protein coupled receptor kinases regulate the activity of G-protein coupled receptors by phosphorylating their intracellular domains after their associated G-proteins have been released and activated. The phosphorylated serines and threonine residues act as binding sites for Arrestin proteins which prevent the reassociation of the G-proteins with their receptors, thereby preventing reactivation of the signaling pathway.
Information are taken from Wikipedia, the open encyclopedia, to which contribute many volunteers from around the whole world. Texts are available under the following conditions GNU Free Documentation License.
Encyklopedie (cz) Encyklopédia (sk) Enzyklopädie (de)