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G protein-coupled receptor



G protein-coupled receptors (GPCRs), also known as seven transmembrane receptors, 7TM receptors, heptahelical receptors, and G protein linked receptors (GPLR), are a protein family of transmembrane receptors that transduce an extracellular signal (ligand binding) into an intracellular signal (G protein activation). The GPCRs are the largest protein family known, members of which are involved in all types of stimulus-response pathways, from intercellular communication to physiological senses.



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