Encyclopedia > G > GDP-fucose Protein O-fucosyltransferase 1
GDP-fucose Protein O-fucosyltransferase 1
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) is an enzyme responsible for adding fucose sugars in O linkage to serine or threonine residues between the second and third conserved cysteines in EGF-like repeats on the Notch protein. The protein is an inverting glycosyltransferase, which means that the enzyme uses GDP-β-L-fucose as a donor substrate and transfers the fucose in O linkage to the protein producing fucose-α-O-serine/threonine.
Information are taken from Wikipedia, the open encyclopedia, to which contribute many volunteers from around the whole world. Texts are available under the following conditions GNU Free Documentation License.
Encyklopedie (cz) Encyklopédia (sk) Enzyklopädie (de)