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Lecithin-cholesterol acyltransferase
Lecithin-cholesterol acyltransferase (LCAT, also called phosphatidylcholine-sterol O-acyltransferase) is an enzyme which converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol) which is then sequestered into the core of a lipoprotein particle eventually making the newly synthesized HDL spherical. The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma
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