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P-glycoprotein
P-glycoprotein (abbreviated as P-gp or Pgp, also called ABCB1, ATP-binding cassette sub-family B member 1, MDR1, P-glycoprotein, and PGY1) is a well characterized human ABC-transporter of the MDR/TAP subfamily. It is extensively distributed and expressed in normal cells such as those lining the intestine, liver cells, renal proximal tubular cells, and capillary endothelial cells comprising the blood brain barrier.
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